Key result
Intravenous administration of 700 mEq of sodium bicarbonate failed to resolve a Brugada electrocardiographic pattern induced by amitriptyline intoxication in a 50-year-old male.
Why the study?
Does sodium bicarbonate resolve amitriptyline-induced Brugada pattern in a patient with tricyclic antidepressant intoxication?
Case Report (n=1)
Does sodium bicarbonate resolve amitriptyline-induced Brugada pattern in a patient with tricyclic antidepressant intoxication?
This case report demonstrates that an amitriptyline-induced Brugada pattern may not respond to high-dose sodium bicarbonate therapy, resolving only with time.
No takes yet. Share an insight, caveat, or question.
Sodium bicarbonate may not resolve amitriptyline-induced Brugada pattern; leaves open questions on optimal TCA intoxication management.
Bebarta et al. (2007) conducted a case report in Amitriptyline intoxication with Brugada electrocardiographic pattern (n=1). Sodium bicarbonate was evaluated on Resolution of Brugada electrocardiographic pattern. Intravenous administration of 700 mEq of sodium bicarbonate failed to resolve a Brugada electrocardiographic pattern induced by amitriptyline intoxication in a 50-year-old male.
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