Population
Rabbit soleus and tibialis anterior muscles
Comparison
28-day indirect stimulation vs Normal tibialis anterior muscle and soleus muscle
Design
Preclinical
Follow-up
28 days
Authors
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Supports early transcriptional plasticity in stimulated muscle; leaves open complete slow myosin maturation and clinical translation.
Chronic stimulation of fast twitch muscle induces transcriptional changes leading to the expression of both fast and slow myosin light chain mRNAs.
Heilig et al. (1983) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: