Why the study?
Does acetazolamide alter arterial-venous glucose and potassium differences following oral glucose loading in normal subjects?
Population
8 normal subjects
Design
Other
Follow-up
72 hours
Authors
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Acetazolamide may alter muscle glucose and potassium handling after loading in normals; leaves open mechanistic basis for benefit in hypokalemic periodic paralysis.
Does acetazolamide alter arterial-venous glucose and potassium differences following oral glucose loading in normal subjects?
Acetazolamide increases glucose uptake and decreases potassium uptake across muscle following glucose ingestion, which may explain its benefit in hypokalemic periodic paralysis.
Jack E. Riggs (1984) studied this question.
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