Key result
Advanced age is linked to higher in-hospital mortality and complications following PCI.
Why the study?
Although age strongly predicts outcomes after PCI, contemporary data in patients of very advanced age remain limited.
Does advanced age increase the risk of in-hospital mortality and complications in patients undergoing percutaneous coronary intervention?
Population
1,454,940 PCI procedures in Japan
Comparison
Age categories 20 to 69 vs 70 to 79 vs 80 to 89 vs 90 to 99 years across AMI and non-AMI indications
Design
Nationwide registry study
Authors
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Advanced age was associated with higher PCI risks; extends prior evidence on age-related outcomes in a large contemporary cohort.
Cohort (n=1,454,940)
Yes
Does advanced age increase the risk of in-hospital mortality and complications in patients undergoing percutaneous coronary intervention?
The age of patients undergoing PCI is consistently increasing, and advanced age, particularly ≥90 years, is strongly associated with higher in-hospital mortality and complications, highlighting the need for shared decision-making.
Saito et al. (2026) conducted a cohort in Acute myocardial infarction (AMI) and non-AMI requiring percutaneous coronary intervention (n=1,454,940). Advanced age vs. Younger age (20 to 69 years) was evaluated on In-hospital mortality and complications. Advanced age was associated with increased in-hospital mortality and complications among 1,454,940 PCI procedures, with nonagenarians comprising 5.0% of the AMI cohort in 2024.