Key result
Nonagenarians undergoing PCI had a significantly higher risk of in-hospital mortality compared to sexagenarians in both ACS (OR 3.60; 95% CI 3.10-4.18) and non-ACS settings.
Why the study?
Scarce data exist regarding outcomes after PCI in elderly patients, particularly nonagenarians.
Does older age (especially ≥90 years) increase the risk of in-hospital mortality and complications in patients undergoing PCI compared to sexagenarians?
Population
562 640 patients aged ≥60 years undergoing PCI from 1018 Japanese hospitals
Comparison
Sexagenarians vs septuagenarians vs octogenarians vs nonagenarians
Design
Prospective nationwide registry study
Follow-up
In-hospital
Authors
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Heightened in-hospital mortality risk in nonagenarians undergoing PCI warrants individualized selection; leaves open optimal strategies and prospective validation.
Observational (n=562,640)
Yes
Does older age (especially ≥90 years) increase the risk of in-hospital mortality and complications in patients undergoing PCI compared to sexagenarians?
Odds Ratio: 3.6 (95% CI 3.1–4.18)
In a large Japanese registry, nonagenarians undergoing PCI had substantially higher risks of in-hospital mortality and bleeding compared to sexagenarians, though transradial access was associated with reduced risk.
Numasawa et al. (2019) conducted an observational in Percutaneous coronary intervention (PCI) (n=562,640). Age ≥90 years (nonagenarians) vs. Sexagenarians was evaluated on In-hospital mortality in acute coronary syndrome (ACS) (OR 3.60, 95% CI 3.10-4.18). Nonagenarians undergoing PCI had a significantly higher risk of in-hospital mortality compared to sexagenarians in both ACS (OR 3.60; 95% CI 3.10-4.18) and non-ACS settings.
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