Why the study?
Does a pH-triggered pacemaker appropriately adjust stimulation rate in response to metabolic needs in a patient requiring pacing?
Does a pH-triggered pacemaker appropriately adjust stimulation rate in response to metabolic needs in a patient requiring pacing?
A pH-triggered pacemaker successfully adjusted pacing rates in response to metabolic stressors over a one-year follow-up in a single patient.
Supports exploration of pH-triggered pacing for metabolic demands; hypothesis-generating and should not yet change practice.
A cardiac pacemaker capable of responding to blood acidosis by change in its stimulation rate allows adjustment to a patient's metabolic needs. The blood pH is sensed by an iridium oxide electrode in the right atrium. During exercise, the venous pH decreases and the paced ventricular rate increases. If acidosis persists, the paced rate gradually returns to baseline and reaches it after about 70 minutes. A pH-triggered pacemaker has been implanted in a 72-year-old male. The pacemaker remained responsive one year after implant, increasing rate during exercise, cold pressor stress, ischemia of the arms and emotional stress.
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Cammilli et al. (1978) studied this question.
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