Why the study?
Does endothelin elicit a positive inotropic effect in isolated guinea-pig atria or papillary muscle?
Does endothelin elicit a positive inotropic effect in isolated guinea-pig atria or papillary muscle?
Endothelin does not exert a positive inotropic effect on guinea-pig atrial or ventricular muscle, challenging previous reports.
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Endothelin shows no positive inotropy in guinea-pig myocardium; challenges prior reports but leaves open human relevance.
Volkmann et al. (1990) studied this question.
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