Key result
Cardiac arrest in a porcine model caused intramyocardial PCO2 to increase from 54 to 346 torr and pH to decrease from 7.20 to 6.38 over 11 minutes, inversely correlating with resuscitation success.
Observational (n=16)
In a porcine model of cardiac arrest, intramyocardial PCO2 increases significantly during ischemia and correlates inversely with coronary perfusion pressure and the likelihood of successful resuscitation.
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Severe intramyocardial acidosis may hinder resuscitation success; leaves open its role as a target or monitor in human cardiac arrest.
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Kette et al. (1993) conducted an observational in Cardiac arrest (n=16). Cardiac arrest vs. Prearrest baseline was evaluated on Intramyocardial PCO2 and hydrogen ion concentration. Cardiac arrest in a porcine model caused intramyocardial PCO2 to increase from 54 to 346 torr and pH to decrease from 7.20 to 6.38 over 11 minutes, inversely correlating with resuscitation success.
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