Key result
Verapamil lowered systolic blood pressure more effectively than propranolol in both black (16.9 vs 8.1 mm Hg) and white (19.0 vs 12.7 mm Hg) patients with essential hypertension.
Why the study?
Does verapamil monotherapy improve blood pressure reduction compared to propranolol in black and white patients with essential hypertension?
Population
Black and white patients with essential hypertension
Comparison
Verapamil monotherapy vs Propranolol monotherapy
Design
Other
Authors
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May support verapamil over propranolol for BP lowering across races; hypothesis-generating and requires randomized confirmation.
RCT
Does verapamil monotherapy improve blood pressure reduction compared to propranolol in black and white patients with essential hypertension?
Verapamil monotherapy is more effective than propranolol for lowering blood pressure in both black and white patients with essential hypertension, with equal efficacy across races unlike propranolol.
L. X. Cubeddu (1986) conducted an RCT in essential hypertension. Verapamil vs. Propranolol was evaluated on blood pressure reduction. Verapamil lowered systolic blood pressure more effectively than propranolol in both black (16.9 vs 8.1 mm Hg) and white (19.0 vs 12.7 mm Hg) patients with essential hypertension.
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