Why the study?
Does atrial pressure development correlate with the release of atrial natriuretic factor during exercise in patients with congestive heart failure?
Population
33 patients with congestive heart failure and 42 normal controls
Comparison
Right-sided heart catheterization during supine… vs Normal controls (for resting measurements)
Design
Cross-sectional
Authors
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Supports preserved ANF response to pressure in HF during exercise; hypothesis-generating and should not yet change practice.
Does atrial pressure development correlate with the release of atrial natriuretic factor during exercise in patients with congestive heart failure?
In patients with congestive heart failure, the capability of ANF secretion in response to pressure stimuli is preserved, with left atrial pressure appearing to be the major stimulus during exercise.
Keller et al. (1988) studied this question.
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