Key result
Enterovirus D68 strains isolated from Kansas City in 2018 belong to subclade B3, resembling the 2016 US epidemic strains but differing from the 2014 outbreak B1 strains.
The 2018 EV-D68 strains from Kansas City belong to subclade B3, resembling the 2016 US epidemic strains rather than the 2014 outbreak B1 strains.
Adds 2018 EV-D68 genomes for surveillance; leaves open whether B3 subclade dominance alters clinical outcomes or outbreak risk.
Here, we report 17 nearly complete genome sequences of enterovirus D68 (EV-D68) isolated from Kansas City, MO, in 2018. Phylogenetic analysis suggests that these strains belong to subclade B3, similar to the ones that caused the 2016 epidemics in the United States but different from the 2014 outbreak B1 strains.
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Pakala et al. (2019) studied this question. Enterovirus D68 strains isolated from Kansas City in 2018 belong to subclade B3, resembling the 2016 US epidemic strains but differing from the 2014 outbreak B1 strains.
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