Key result
Oral clonidine premedication at 4 μg/kg reduced sevoflurane-induced agitation scores in children without prolonging the time to meet home discharge criteria.
Why the study?
Does oral clonidine premedication reduce sevoflurane-induced agitation in children undergoing minor surgery?
Population
Children aged 2–11 yr undergoing minor (urological, ophthalmological, otological, and orthopedic) surgery
Comparison
Oral clonidine administered 30–60 min before… vs Midazolam, diazepam, or placebo
Design
Editorial, Blindly recorded agitation score
Follow-up
Until meeting discharge criteria
Authors
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Oral clonidine (4 μg/kg) premedication is an effective alternative to IV clonidine for reducing sevoflurane-induced agitation in children without delaying discharge.
Does oral clonidine premedication reduce sevoflurane-induced agitation in children undergoing minor surgery?
Oral clonidine (4 μg/kg) premedication is an effective alternative to IV clonidine for reducing sevoflurane-induced agitation in children without delaying discharge.
Mikawa et al. (2002) conducted a letter in Sevoflurane-induced agitation. Oral clonidine vs. Midazolam, diazepam, and placebo was evaluated on Agitation score during and after emergence from anesthesia and time to meet discharge criteria. Oral clonidine premedication at 4 μg/kg reduced sevoflurane-induced agitation scores in children without prolonging the time to meet home discharge criteria.
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