November 1, 1995Microvascular ResearchOpen Access

Transmural Distribution of Capillary Morphology as a Function of Coronary Perfusion Pressure in the Resting Canine Heart

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Population

Glutaraldehyde-fixed canine hearts

Design

Preclinical

Authors

KMKaren May‐NewmanUniversidad de Granada OMOdile Mathieu‐CostelloUniversity of California, San Diego JOJeffrey H. OmensHeart Failure / Cardiomyopathy

Discussion

Member takes

Implication

Animal data associate capillary morphology with intramyocardial capacitance; leaves open translation to human coronary physiology.

Structured PICO

Population

Glutaraldehyde-fixed canine hearts

Intervention

Changes in coronary perfusion pressure

Outcome

Transmural variations in coronary capillary geometry (volume fractions, diameter, numerical density, anisotropy, and sarcomere length)surrogate

Intramyocardial capacitance is at least in part associated with nonhomogeneous changes in coronary capillary morphology with altered perfusion pressure.

Cite This Study

May‐Newman et al. (1995) studied this question.

synapsesocial.com/papers/6a98675c193de88970d996da https://doi.org/10.1006/mvre.1995.1066

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Transmural Distribution of Capillary Morphology as a Function of Coronary Perfusion Pressure in the Resting Canine Heart

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Transmural Distribution of Capillary Morphology as a Function of Coronary Perfusion Pressure in the Resting Canine Heart

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider