Why the study?
Does left heart bypass using a variable rate mode improve hemodynamics and regional myocardial blood flow in a goat model of acute left ventricular failure?
Population
12 goats evaluated first with normal ventricles and subsequently with acute left ventricular failure induced…
Comparison
Left heart bypass using a pneumatic pusher-plate… vs Baseline hemodynamics and regional myocardial…
Design
Preclinical
Follow-up
Acute (during bypass)
Authors
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May support output in experimental LV failure but reduce non-infarct myocardial flow; leaves open translation to clinical use.
Does left heart bypass using a variable rate mode improve hemodynamics and regional myocardial blood flow in a goat model of acute left ventricular failure?
Left heart bypass using a variable rate mode effectively supports systemic circulation in acute left ventricular failure, though it decreases regional myocardial blood flow in non-infarcted areas.
Kazuo Shiotsu (1989) studied this question.
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