Key result
Serum ANGPTL8 concentrations were significantly increased in subjects with impaired glucose regulation and type 2 diabetes compared to those with normal glucose tolerance.
Why the study?
Are serum ANGPTL8 concentrations increased in patients with prediabetes and type 2 diabetes compared to those with normal glucose tolerance?
Population
129 subjects including 22 with normal glucose tolerance, 74 with impaired glucose regulation, and 33 with…
Design
Cross-sectional
Authors
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Elevated ANGPTL8 in prediabetes and T2D is hypothesis-generating; cross-sectional data leaves open causality and clinical utility.
Cross-Sectional (n=129)
Are serum ANGPTL8 concentrations increased in patients with prediabetes and type 2 diabetes compared to those with normal glucose tolerance?
Serum ANGPTL8 concentrations are significantly elevated in patients with impaired glucose regulation and type 2 diabetes, suggesting a potential role in the pathological mechanism of glucose intolerance.
Yin et al. (2017) conducted a cross-sectional in Prediabetes and Type 2 Diabetes (n=129). Impaired glucose regulation and Type 2 Diabetes vs. Normal glucose tolerance was evaluated on Serum ANGPTL8 concentrations. Serum ANGPTL8 concentrations were significantly increased in subjects with impaired glucose regulation and type 2 diabetes compared to those with normal glucose tolerance.
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