Why the study?
Does pre-intervention Platelet-to-Lymphocyte Ratio predict angiographic no-reflow in patients with acute STEMI undergoing primary percutaneous coronary intervention?
Population
72 patients with acute ST-segment Elevation Myocardial Infarction occurring within 12 hours of the onset of…
Comparison
High pre-intervention Platelet-to-Lymphocyte Ratio vs Low pre-intervention Platelet-to-Lymphocyte Ratio
Design
Cohort
Key result
Pre-intervention Platelet-to-Lymphocyte Ratio independently predicted no-reflow after primary percutaneous coronary intervention in acute STEMI (OR 1.008; 95% CI 1.002-1.014; p<0.001).
Authors
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PLR may aid no-reflow risk stratification in STEMI PPCI; observational data leaves open prospective validation before practice change.
Observational (n=72)
Does pre-intervention Platelet-to-Lymphocyte Ratio predict angiographic no-reflow in patients with acute STEMI undergoing primary percutaneous coronary intervention?
Odds Ratio: 1.008 (95% CI 1.002–1.014)
p-value: p=<0.001
Pre-intervention platelet-to-lymphocyte ratio is a strong and independent predictor of angiographic slow flow or no-reflow in patients with acute STEMI undergoing primary PCI.
EL-HAWARY et al. (2018) conducted an observational in Acute ST-Segment Elevation Myocardial Infarction (STEMI) (n=72). Platelet-to-Lymphocyte Ratio (PLR) vs. Lower PLR was evaluated on No-reflow after primary percutaneous coronary intervention (OR 1.008, 95% CI 1.002-1.014, p=<0.001). Pre-intervention Platelet-to-Lymphocyte Ratio independently predicted no-reflow after primary percutaneous coronary intervention in acute STEMI (OR 1.008; 95% CI 1.002-1.014; p<0.001).
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