Key result
Stent thrombosis after primary angioplasty for STEMI was a powerful independent predictor of mortality (23.6% vs 6.0%; HR 3.73, 95% CI 2.75-5.07, P<0.001).
Why the study?
Does the use of drug-eluting stents compared to bare metal stents affect the timing and incidence of stent thrombosis, and what is its prognostic significance in STEMI patients undergoing primary angioplasty?
Cohort (n=6,274)
Yes
Does the use of drug-eluting stents compared to bare metal stents affect the timing and incidence of stent thrombosis, and what is its prognostic significance in STEMI patients undergoing primary angioplasty?
Hazard Ratio: 3.73 (95% CI 2.75–5.07)
Absolute Event Rate: 23.6% vs 6%
p-value: p=< 0.001
Stent thrombosis after primary PCI for STEMI occurs in approximately 4.25% of patients up to 6 years post-procedure and is a powerful independent predictor of mortality.
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Prioritizes stent thrombosis prevention after STEMI PCI; confirms its role as a major independent mortality predictor.
Dirksen et al. (2013) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=6,274). Stent thrombosis vs. No stent thrombosis was evaluated on Mortality (HR 3.73, 95% CI 2.75-5.07, p=< 0.001). Stent thrombosis after primary angioplasty for STEMI was a powerful independent predictor of mortality (23.6% vs 6.0%; HR 3.73, 95% CI 2.75-5.07, P<0.001).
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