Key result
Oxygen breathing at 1 atm. reduced resting muscle blood flow, although relative changes may be overestimated when calculated from changes in 133Xe elimination rate constants.
Why the study?
Does oxygen breathing at 1 atm reduce resting muscle blood flow?
Population
Subjects undergoing measurement of resting anterior tibial muscle blood flow
Comparison
Oxygen breathing at 1 atm vs Baseline/room air (implied)
Design
Other
Follow-up
10 to 30 minutes post-injection
Authors
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May reduce resting muscle blood flow with 1 atm oxygen; leaves open accurate quantification by 133Xe without correction for spontaneous changes.
Does oxygen breathing at 1 atm reduce resting muscle blood flow?
Oxygen breathing at 1 atm reduces resting muscle blood flow, but researchers must account for spontaneous decreases in 133Xe elimination rate constants which can lead to overestimation of relative changes.
Hansen et al. (1973) studied Resting muscle blood flow. Oxygen breathing was evaluated on Resting muscle blood flow. Oxygen breathing at 1 atm. reduced resting muscle blood flow, although relative changes may be overestimated when calculated from changes in 133Xe elimination rate constants.