Key result
Major depression was significantly associated with a higher total symptom burden score (Beta 11.74; 95% CI 9.24-14.23) among older patients hospitalized for heart failure.
Why the study?
The study was conducted to assess the symptom burden among older patients hospitalised for heart failure.
Cross-Sectional (n=314)
No
Effect estimate: Beta 11.74 (95% CI 9.24-14.23)
Older patients hospitalized for heart failure experience a high symptom burden, with major depression significantly associated with both total symptom burden and lower LVEF, highlighting the need for palliative care approaches.
Supports depression screening in older HF inpatients; hypothesis-generating for whether treatment reduces symptom burden.
This study aimed to assess the symptom burden among older patients hospitalised for heart failure. This hospital-based, cross-sectional study was conducted at the National Geriatric Hospital, Hanoi, Vietnam, from June 2019 to August 2020. Face-to-face interviews were performed to gather the following information: socio-demographic characteristics, heart failure classification, and clinical characteristics (comorbidities, polypharmacy, pro–B-type natriuretic peptide, left ventricular ejection fraction (LVEF), symptom burden, and depression). Symptom burden was assessed using the Edmonton Symptom Assessment Scale (ESAS), and depression was measured using the Patient Health Questionnaire. A total of 314 patients participated in the study. The mean participant age was 72.67 (SD = 9.42) years. The most frequently reported symptoms on the ESAS were shortness of breath (95.5%), fatigue (94.8%), and anxiety (81.2%). In univariate analyses, depression was significantly associated with heart failure class (p < 0.05). Multivariate linear regression revealed that major depression was significantly associated with total symptom burden score (Beta: 11.74; 95% CI: 9.24–14.23) and LVEF (Beta: −0.09; 95% CI: −0.17–(−0.007)). Patients hospitalised for heart failure experienced a high burden of symptoms. Further studies addressing adverse outcomes and expanding to community-dwelling older people are essential. Palliative care approaches that target symptom reduction should be considered in patients with heart failure.
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Nguyen et al. (2022) conducted a cross-sectional in Heart failure (n=314). Major depression was evaluated on Total symptom burden score (Beta 11.74, 95% CI 9.24-14.23). Major depression was significantly associated with a higher total symptom burden score (Beta 11.74; 95% CI 9.24-14.23) among older patients hospitalized for heart failure.
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