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August 1, 1993Clinical Infectious Diseases

Mycoplasmal Pericarditis: Evidence of Invasive Disease

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Key result

Appropriate antibiotic therapy was uniformly effective in treating five patients with mycoplasmal pericarditis, demonstrating an invasive pathogenesis for this syndrome.

Population

5 patients with large pericardial effusions and confirmed mycoplasmal pericarditis, of whom 4 were…

Design

Case_series

Authors

RKRichard T. KenneyJacksonville UniversityJLJennifer S. LiPediatric / Congenital CardiologyWCWallace A. ClydeUniversity of North Carolina at Chapel Hill

Discussion

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Implication

May support considering mycoplasmal pericarditis in high-risk patients; leaves open need for prospective validation before routine screening.

Study Design

Type

Case Report (n=5)

Structured PICO

P
Population
5 patients with mycoplasmal pericarditis, 4 of whom were immunocompromised or had prior cardiac surgery.
E
Exposure
Appropriate antibiotic therapy and aggressive diagnostic culture of pericardial tissue and/or fluid.
O
Outcome
Positive culture of pericardial tissue and/or fluid and clinical response to antibiotic therapy.

Mycoplasmal pericarditis is an invasive disease that responds uniformly to appropriate antibiotics and should be actively sought, especially in patients who are immunocompromised or have undergone prior cardiac surgery.

Cite This Study

Kenney et al. (1993) conducted a case report in Mycoplasmal Pericarditis (n=5). Antibiotic therapy was evaluated on Clinical response to antibiotic therapy. Appropriate antibiotic therapy was uniformly effective in treating five patients with mycoplasmal pericarditis, demonstrating an invasive pathogenesis for this syndrome.

synapsesocial.com/papers/6a99ce71a2ec1cee3d4d2525https://doi.org/10.1093/clinids/17.supplement_1.s58

Topics

Pericardial disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pericarditis and Perimyocarditis Associated with Active Mycoplasma pneumoniae Infection1977 · 84 citations
  2. 2Carditis Associated with Mycoplasma Pneumoniae Infection1979 · 64 citations
  3. 3Isolation of Mycoplasma Hominis from Cerebrospinal Fluid1973 · 33 citations
  4. 4Immunologic Interactions Between Host Cells and Mycoplasmas: An Introduction1982 · 15 citations
  5. 5Interaction of Mycoplasma pneumoniae with erythrocyte glycolipids of I and i antigen types1985 · 69 citations