Key result
Coxsackie B-1 virus can become lethal for weanling and adult nonconditioned mice while retaining its cytopathogenic effect and ability to be neutralized by specific antiserum.
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Broadens adult mouse models for Coxsackie myocarditis research; hypothesis-generating with uncertain human translation.
Coxsackie B-1 virus can become lethal for weanling and adult nonconditioned mice. This property is not gained at the expense of other characteristics, specifically cytopathogenic effect in monkey kidney cell cultures and ability to be neutralized by specific antiserum.
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Grunberg et al. (1963) studied this question. Coxsackie B-1 virus can become lethal for weanling and adult nonconditioned mice while retaining its cytopathogenic effect and ability to be neutralized by specific antiserum.
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