Key result
Serum procalcitonin and C-reactive protein levels were significantly elevated in patients with post-operative infections, with procalcitonin being a more sensitive and specific marker.
Why the study?
Major hepatobiliary surgeries carry a high risk for post-operative sepsis, but serum CRP and PCT as early markers had not been evaluated in this setting or in the Indian subcontinent.
Are serum C-reactive protein and procalcitonin effective early markers for diagnosing post-operative infection in patients undergoing hepatobiliary surgery?
Cross-Sectional (n=42)
No
Are serum C-reactive protein and procalcitonin effective early markers for diagnosing post-operative infection in patients undergoing hepatobiliary surgery?
p-value: p=0.02
Serum procalcitonin is a highly sensitive and specific early marker for post-operative infection following hepatobiliary surgery, outperforming C-reactive protein.
May aid early post-hepatobiliary complication detection; leaves open prospective validation before practice change.
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CC et al. (2020) conducted a cross-sectional in Post-operative infection after hepato-biliary surgery (n=42). Serum Procalcitonin and C-reactive protein vs. Uninfected patients was evaluated on Diagnosis of post-operative infection (p=0.02). Serum procalcitonin and C-reactive protein levels were significantly elevated in patients with post-operative infections, with procalcitonin being a more sensitive and specific marker.
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