Key result
Hancock porcine bioprosthetic heart valves had a probable effective life of 10 years before structural failure increased, with markedly diminished degeneration in patients aged ≥70 years.
Cohort (n=1,533)
No
The Hancock porcine bioprosthetic valve has an effective life of about 10 years, making it particularly suitable for elderly patients (≥70 years) who experience less structural degeneration, or those with contraindications to anticoagulation.
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May inform age-based bioprosthetic valve selection; leaves open randomized confirmation of durability.
Cohn et al. (1989) conducted a cohort in Valvular heart disease (n=1,533). Hancock porcine bioprosthetic heart valve replacement was evaluated on Morbidity, mortality, and probability of reoperation for structural valve failure. Hancock porcine bioprosthetic heart valves had a probable effective life of 10 years before structural failure increased, with markedly diminished degeneration in patients aged ≥70 years.
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