Key result
Hancock bovine pericardial valves exhibited premature structural failure, with 25% of patients requiring re-replacement and a 54% actuarial freedom from valve-related complications at 60 months.
Population
122 patients who received 129 Hancock bovine pericardial valves between May 1982 and April 1985, mean age 56…
Design
Cohort
Follow-up
Mean 44 months (maximum 66 months)
Authors
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Hancock valves may warrant enhanced surveillance for early failure; Level 3 data leaves open comparative durability versus alternatives.
Cohort (n=122)
No
Hancock bovine pericardial valves exhibit premature structural failure due to vertical shear, necessitating frequent re-replacement and supporting the manufacturer's shelf recall.
Scully et al. (1988) conducted a cohort in Valvular heart disease requiring valve replacement (n=122). Hancock bovine pericardial valves was evaluated on Actuarial freedom from valve-related complications at 60 months. Hancock bovine pericardial valves exhibited premature structural failure, with 25% of patients requiring re-replacement and a 54% actuarial freedom from valve-related complications at 60 months.
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