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March 8, 2010European Journal of Cardio-Thoracic SurgeryOpen Access

The fate of Hancock II porcine valve recipients 25 years after implant☆

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Key result

The Hancock II bioprosthesis demonstrated 20-year freedom from re-operation of 86.8% in older (≥60 years) and 52.2% in younger (<60 years) aortic valve replacement patients (p<0.0001).

Why the study?

What are the long-term survival and freedom from re-operation rates in patients receiving the Hancock II porcine bioprosthesis?

Population

517 consecutive patients undergoing valve replacement surgery between May 1983 and November 1993. 106…

Design

Cohort

Follow-up

median 12 years (range: 0-25)

Authors

CVCarlo ValfrèCa' Foncello HospitalPIPaolo IusCa' Foncello HospitalGMGiuseppe MinnitiPoliclinico Umberto I

Discussion

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Overview

Supports age-stratified AVR decisions with Hancock II; leaves open randomized comparisons to newer bioprostheses.

Study Design

Type

Cohort (n=517)

Structured PICO

What are the long-term survival and freedom from re-operation rates in patients receiving the Hancock II porcine bioprosthesis?

P
Population
517 patients (mean age 64 years) undergoing aortic or mitral valve replacement with the Hancock II porcine bioprosthesis, followed for a median of 12 years.
E
Exposure
Valve replacement with Hancock II porcine bioprosthesis
O
Outcome
Long-term survival and freedom from re-operation at up to 25 yearshard clinical

The Hancock II porcine bioprosthesis demonstrates excellent long-term durability, with 20-year freedom from re-operation of 79.3% in aortic and 52.8% in mitral positions.

Cite This Study

Valfrè et al. (2010) conducted a cohort in Aortic or mitral valve replacement (n=517). Hancock II porcine bioprosthesis was evaluated on Long-term survival and freedom from re-operation. The Hancock II bioprosthesis demonstrated 20-year freedom from re-operation of 86.8% in older (≥60 years) and 52.2% in younger (<60 years) aortic valve replacement patients (p<0.0001).

synapsesocial.com/papers/6a9ed8d480ddd97117f0c8a5https://doi.org/10.1016/j.ejcts.2010.01.046

Topics

Valvular heart disease
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease2006 · 8,514 citations
  2. 2Guidelines for the Management of Patients With Valvular Heart Disease1998 · 1,041 citations