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December 1, 1991Journal of Cardiac Surgery

The Long-Term Follow-Up of the Hancock Modified Orifice Porcine Bioprosthetic Valve

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Key result

Isolated aortic valve replacement with the Hancock Modified Orifice porcine bioprosthetic valve was associated with a 2% operative mortality rate over a mean follow-up of 7.4 years.

Population

305 patients undergoing isolated aortic valve replacement between 1976 and 1985, with a mean functional…

Design

Cohort

Follow-up

6-14 years (mean 7.4 years)

Authors

LCLawrence H. CohnInterventional / Structural CardiologyGCGregory S. CouperHeart Failure / CardiomyopathySASary F. ArankiCardiac Surgery

Discussion

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Overview

Supports Hancock valve consideration in isolated AVR; extends observational follow-up data to 14 years but requires prospective validation.

Study Design

Type

Cohort (n=305)

Multicenter

No

Structured PICO

P
Population
305 patients undergoing isolated aortic valve replacement with the Hancock Modified Orifice valve, followed for a mean of 7.4 years.
E
Exposure
Hancock Modified Orifice porcine bioprosthetic valve implantation
O
Outcome
10-year actuarial survival freedom from reoperation, thromboembolism, structural valve degeneration, perivalvular leak, infectious valve degeneration, and total morbidity and mortalityhard clinical

The Hancock Modified Orifice porcine bioprosthetic valve demonstrated a 2% operative mortality in isolated aortic valve replacements, with long-term follow-up data provided up to 14 years.

Cite This Study

Cohn et al. (1991) conducted a cohort in Aortic valve disease requiring replacement (n=305). Hancock Modified Orifice porcine bioprosthetic valve was evaluated on Operative mortality. Isolated aortic valve replacement with the Hancock Modified Orifice porcine bioprosthetic valve was associated with a 2% operative mortality rate over a mean follow-up of 7.4 years.

synapsesocial.com/papers/6a9e705e8f37065ff4e98275https://doi.org/10.1111/jocs.1991.6.4s.557
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Fifteen-Year Experience with 1678 Hancock Porcine Bioprosthetic Heart Valve Replacements1989 · 114 citations