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August 1, 1979Circulation

Long-term follow-up of the Hancock bioprosthetic heart valve: a 6-year review.

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Key result

Hancock porcine bioprosthetic valves demonstrate ~6% operative mortality and low thromboembolism rates.

  • n=467

Why the study?

Long-term clinical experience and durability data for the Hancock porcine bioprosthetic heart valve were needed to assess survival, thromboemboli, and valve function.

What are the long-term survival, thromboembolic risk, and durability of the Hancock porcine bioprosthetic heart valve?

Population

467 patients receiving 528 Hancock porcine bioprosthetic heart valves

Design

Cohort study

Follow-up

Average 33 months (range 16-75 months)

Authors

LCL H CohenJKJ. Kenneth KosterThe University of Texas Health Science Center at San AntonioRMRoger B.B. MeeRoyal Children's Hospital

Discussion

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Overview

Supports durability data for Hancock valve in non-AF patients; extends observational reports but leaves open randomized comparisons.

Study Design

Type

Cohort (n=467)

Structured PICO

What are the long-term survival, thromboembolic risk, and durability of the Hancock porcine bioprosthetic heart valve?

P
Population
467 patients (mean age 56 years) who received Hancock porcine bioprosthetic heart valves, followed for an average of 33 months.
E
Exposure
Hancock porcine bioprosthetic heart valve replacement (aortic, mitral, or multiple)
O
Outcome
Operative mortality, long-term survival, thromboemboli, and primary valve dysfunctionhard clinical

The Hancock porcine bioprosthetic heart valve demonstrates acceptable durability over 6 years with a low incidence of thromboemboli in patients without chronic atrial fibrillation.

Cite This Study

Cohen et al. (1979) conducted a cohort in Valvular heart disease requiring valve replacement (n=467). Hancock porcine bioprosthetic heart valve was evaluated on Overall operative mortality. The Hancock porcine bioprosthetic heart valve demonstrated an overall operative mortality of 5.6% and actuarial survival of 75.7% to 79% at 66-75 months, with a low incidence of thromboemboli.

synapsesocial.com/papers/6aaa2d5a33211e1322fca16fhttps://doi.org/10.1161/01.cir.60.2.87

Topics

Valvular heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Long-Term Follow-Up of the Hancock Modified Orifice Porcine Bioprosthetic Valve1991 · 15 citations
  2. 2Five-Year Follow-up of Hancock Pericardial Valves: Management of Premature Failure1988 · 6 citations
  3. 3Fifteen-Year Experience with 1678 Hancock Porcine Bioprosthetic Heart Valve Replacements1989 · 114 citations
  4. 4Early clinical experience with the Hancock porcine xenograft valve prosthesis.1979 · 1 citations
  5. 5Extended Follow-Up of the Standard Hancock Porcine Bioprosthesis1991 · 16 citations