Key result
A simple cross-linking reaction through ionic interaction may be the primary cause of the heparin-accelerated antithrombin inhibition of α-thrombin.
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Does not alter heparin use in practice; leaves open in vivo validation of ionic cross-linking mechanism.
Emerging evidence suggests that a simple cross‐linking reaction through ionic interaction may be the primary cause of the heparin‐accelerated antithrombin inhibition of α‐thrombin.
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Jui‐Yoa Chang (1984) studied this question. A simple cross-linking reaction through ionic interaction may be the primary cause of the heparin-accelerated antithrombin inhibition of α-thrombin.
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