Key result
Kussmaul physiology in patients with advanced heart failure was associated with a higher incidence of post-transplant right ventricular failure and overall mortality (P<0.05).
Why the study?
Does the presence of Kussmaul physiology predict adverse clinical outcomes and hemodynamics in patients with severe heart failure referred for transplantation?
Population
90 ambulant patients with congestive heart failure referred for assessment for heart transplantation, mean…
Comparison
Presence of Kussmaul physiology vs Absence of Kussmaul physiology
Design
Cohort
Follow-up
mean 379±227 days
Authors
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May inform pre-transplant risk assessment in advanced HF; leaves open whether it should guide decisions pending prospective validation.
Cohort (n=90)
No
Does the presence of Kussmaul physiology predict adverse clinical outcomes and hemodynamics in patients with severe heart failure referred for transplantation?
p-value: p=<0.05
Kussmaul physiology is common in advanced heart failure patients and is associated with worse hemodynamics and higher mortality, suggesting its utility in pre-transplant assessment.
Nadir et al. (2014) conducted a cohort in Congestive heart failure (n=90). Kussmaul physiology vs. Without Kussmaul physiology was evaluated on Post-transplant right ventricular failure and overall mortality (p=<0.05). Kussmaul physiology in patients with advanced heart failure was associated with a higher incidence of post-transplant right ventricular failure and overall mortality (P<0.05).
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