Why the study?
Can Doppler echocardiography noninvasively identify restrictive-constrictive physiology and its clinical correlates in long-term cardiac allograft recipients?
Can Doppler echocardiography noninvasively identify restrictive-constrictive physiology and its clinical correlates in long-term cardiac allograft recipients?
Doppler echocardiography can noninvasively identify restrictive-constrictive physiology, which occurs in approximately 15% of cardiac allograft recipients and is associated with impaired systolic performance and higher rejection incidence.
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May flag elevated rejection risk via Doppler in long-term allografts; leaves open prospective validation before screening adoption.
Valantine et al. (1989) studied this question.
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