Key result
Bileaflet prostheses required less total energy for stroke and closure compared to tilting disc valves in a simulated double valve replacement model.
Why the study?
Do bileaflet valves and larger valve sizes improve hydrodynamic performance compared to tilting disc valves and smaller sizes in a double valve replacement simulator?
Population
In vitro pulsatile flow simulator reproducing physiological ventricular dynamics to match input and output…
Comparison
Carbomedics bileaflet valves combined with small… vs Bjork Shiley tilting disc valves combined with…
Design
Preclinical
Authors
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In vitro efficiency data warrant clinical trials; leaves open whether bileaflet valves improve outcomes in double valve replacement.
Do bileaflet valves and larger valve sizes improve hydrodynamic performance compared to tilting disc valves and smaller sizes in a double valve replacement simulator?
In an in vitro model of double valve replacement, bileaflet prostheses and larger mitral valves (when paired with large aortic valves at high flow) offer better hydrodynamic efficiency.
Strüber et al. (1996) studied Double valve replacement. Bileaflet valves (Carbomedics) vs. Tilting disc valves (Bjork Shiley) was evaluated on Hydrodynamic performance (stroke work, closing work, and leak work). Bileaflet prostheses required less total energy for stroke and closure compared to tilting disc valves in a simulated double valve replacement model.
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