Key result
Bovine enterovirus replicates and produces cytopathic effects in human U937 and ZR-75-1 cancer cell lines to the same extent as in standard propagation cells.
Why the study?
Does bovine enterovirus replicate and cause cytopathic effect in human tumour cell lines?
Population
Freshly isolated human monocytes, monocyte-derived macrophages, monocyte-like U937 tumour cell line…
Design
Preclinical
Authors
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May support oncolytic virotherapy exploration; leaves open clinical translation pending in vivo and human studies.
Does bovine enterovirus replicate and cause cytopathic effect in human tumour cell lines?
Bovine enterovirus shows potential as an anti-tumour agent by replicating and causing cytopathic effects in human cancer cell lines.
Smyth et al. (2002) studied Cancer. Bovine enterovirus was evaluated on Viral replication and cytopathic effect. Bovine enterovirus replicates and produces cytopathic effects in human U937 and ZR-75-1 cancer cell lines to the same extent as in standard propagation cells.
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