Key result
Consanguineous marriage was significantly associated with an increased risk of congenital heart disease in offspring (OR 1.551; 95% CI 1.138-2.113; P=0.033).
Why the study?
Does consanguineous marriage increase the risk of congenital heart disease in offspring?
Case-Control (n=200)
No
Does consanguineous marriage increase the risk of congenital heart disease in offspring?
Odds Ratio: 1.551 (95% CI 1.138–2.113)
Absolute Event Rate: 14% vs 5%
p-value: p=0.033
Consanguineous marriage is a significant risk factor for the development of congenital heart disease in offspring.
No takes yet. Share an insight, caveat, or question.
May warrant inclusion in preconception counseling; leaves open prospective confirmation of causality.
Fazeriandy et al. (2018) conducted a case-control in Congenital heart disease (n=200). Consanguineous marriage vs. Non-consanguineous marriage was evaluated on Congenital heart disease (OR 1.551, 95% CI 1.138-2.113, p=0.033). Consanguineous marriage was significantly associated with an increased risk of congenital heart disease in offspring (OR 1.551; 95% CI 1.138-2.113; P=0.033).
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