Key result
Parental consanguinity was identified as a major risk factor for congenital heart disease, present in 86% of cases compared to 40% of controls.
Why the study?
Congenital heart diseases are multifactorial in etiology, and consanguinity could increase the likelihood of congenital heart disease.
Does parental consanguinity increase the risk of congenital heart disease in children aged 0-12 years?
Case-Control (n=100)
Does parental consanguinity increase the risk of congenital heart disease in children aged 0-12 years?
Absolute Event Rate: 86% vs 40%
No takes yet. Share an insight, caveat, or question.
Parental consanguinity is a significant risk factor for congenital heart disease in children, with VSD being the most common defect.
Tiriya et al. (2021) conducted a case-control in Congenital heart disease (n=100). Consanguinity vs. No consanguinity was evaluated on Parental consanguinity. Parental consanguinity was identified as a major risk factor for congenital heart disease, present in 86% of cases compared to 40% of controls.
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