Key result
Immunization of chickens or rabbits with affinity-chromatography purified glycoproteins of Marek's disease virus and herpesvirus of turkeys resulted in the production of neutralizing antibodies.
Population
Chickens or rabbits (preclinical model) and Marek's disease virus/herpesvirus of turkeys
Design
Preclinical
Authors
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Glycoprotein immunization elicits neutralizing antibodies in avian models; leaves open protective efficacy and field translation for Marek's disease vaccines.
Identification and immunization with specific glycoproteins from Marek's disease virus and herpesvirus of turkeys can induce neutralizing antibodies in animal models.
Ikuta et al. (1984) studied Marek's disease virus and herpesvirus of turkeys. Immunization with purified glycoproteins was evaluated on Production of neutralizing antibodies. Immunization of chickens or rabbits with affinity-chromatography purified glycoproteins of Marek's disease virus and herpesvirus of turkeys resulted in the production of neutralizing antibodies.
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