Key result
SK&F 30097, a triazinoindole, exerts selective antiviral activity against picornaviruses in vitro by specifically inhibiting viral RNA synthesis.
Population
picornaviruses in vitro
Design
Preclinical
Authors
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Supports preclinical picornavirus antiviral development; leaves open in vivo efficacy and clinical translation.
SK&F 30097 demonstrates selective in vitro antiviral activity against picornaviruses via inhibition of viral RNA synthesis.
Matsumoto et al. (1972) studied this question. SK&F 30097, a triazinoindole, exerts selective antiviral activity against picornaviruses in vitro by specifically inhibiting viral RNA synthesis.
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