Key result
Maternal ingestion of warfarin during pregnancy resulted in fetal warfarin syndrome characterized by an absent nasal bone, depressed nasal bridge, stippled vertebrae, and congenital heart defects in the neonate.
Why the study?
Does maternal ingestion of warfarin during pregnancy cause congenital abnormalities?
Population
A baby born to a mother who ingested warfarin during pregnancy
Design
Case_report
Authors
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Warrants caution with warfarin in women of childbearing age; extends case reports of fetal warfarin syndrome.
Case Report (n=1)
No
Does maternal ingestion of warfarin during pregnancy cause congenital abnormalities?
Warfarin therapy in women of childbearing age carries a known risk of teratogenic effects, specifically fetal warfarin syndrome, which cardiologists and obstetricians must consider.
Prithviraj et al. (2014) conducted a case report in Fetal Warfarin Syndrome (n=1). Warfarin was evaluated on Congenital abnormalities (Fetal Warfarin Syndrome). Maternal ingestion of warfarin during pregnancy resulted in fetal warfarin syndrome characterized by an absent nasal bone, depressed nasal bridge, stippled vertebrae, and congenital heart defects in the neonate.
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