Key result
Inspiratory resistive loading altered total variational activity of breathing, decreasing the random fraction with a 3 cm H2O/L/s load and increasing it with a 6 cm H2O/L/s load.
Why the study?
Does inspiratory resistive loading alter the variational activity of breathing in healthy subjects?
Population
18 healthy subjects
Comparison
Inspiratory resistive loads of 3 and 6 cm… vs Resting breathing
Design
Other, applied randomly
Follow-up
1 h each
Authors
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Resistive loading modulates breathing variability by load in healthy subjects; leaves open translation to clinical respiratory disorders.
RCT (n=18)
Randomly applied crossover
Does inspiratory resistive loading alter the variational activity of breathing in healthy subjects?
Inspiratory resistive loading alters the variational activity of breathing in healthy subjects, with different load sizes producing distinct effects on random and correlated variability.
Brack et al. (1998) conducted an RCT in Healthy (n=18). Inspiratory resistive loading vs. Resting breathing was evaluated on Variational activity of breathing (total variational activity, random uncorrelated fraction, and correlated behavior). Inspiratory resistive loading altered total variational activity of breathing, decreasing the random fraction with a 3 cm H2O/L/s load and increasing it with a 6 cm H2O/L/s load.
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