Key result
Inspiratory elastic loading of 18 cm H2O/L decreased the gross variability of tidal volume and expiratory time (p<0.01) but increased the variability of inspiratory time (p<0.03).
Why the study?
Does inspiratory elastic loading alter the variational activity of breathing in healthy subjects?
RCT (n=11)
Randomized
Does inspiratory elastic loading alter the variational activity of breathing in healthy subjects?
p-value: p=<0.01
Elastic loading alters the gross variability of primary breath components by changing the random fraction of variational activity, possibly reflecting an attempt to compensate for the load while minimizing dyspnea.
No takes yet. Share an insight, caveat, or question.
May alter breathing variability in healthy subjects; leaves open effects and relevance in respiratory disease.
Brack et al. (1997) conducted an RCT in Healthy (n=11). Inspiratory elastic loads vs. Rest was evaluated on Gross variability (standard deviation) of tidal volume (VT) and expiratory time (TE) (p=<0.01). Inspiratory elastic loading of 18 cm H2O/L decreased the gross variability of tidal volume and expiratory time (p<0.01) but increased the variability of inspiratory time (p<0.03).
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