Key result
Small mechanical loads added to the external airway immediately altered breathing patterns, reducing minute ventilation and mean inspiratory flow even when imperceptible.
Population
Human subjects
Design
Other
Authors
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Highlights need to control for subtle loads in respiratory research; leaves open clinical relevance in disease.
Imperceptible mechanical loads on the airway elicit immediate breathing pattern changes, likely reflecting subconscious neural reflexes and intrinsic respiratory muscle characteristics.
Daubenspeck et al. (1983) studied this question. Small mechanical loads (flow-resistive and elastic) was evaluated on Breathing pattern responses (tidal volume, expiratory duration, inspiratory duration, respiratory frequency, minute ventilation, mean inspiratory flow). Small mechanical loads added to the external airway immediately altered breathing patterns, reducing minute ventilation and mean inspiratory flow even when imperceptible.
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