Key result
Severe expiratory resistive loads (18 cmH2O.l-1.s) significantly increased occlusion pressure responses to CO2 and enhanced inspiratory muscle activity compared to control in healthy subjects.
Why the study?
What are the effects of expiratory resistive loads on ventilation and occlusion pressure responses to CO2 in healthy subjects?
Population
healthy subjects
Comparison
expiratory resistive loads of 10 and 18… vs inspiratory resistive load of 10 cmH2O.l-1.s and…
Design
Other
Authors
Loading...
May alter ventilatory drive in obstructive disease; leaves open translation to clinical populations.
What are the effects of expiratory resistive loads on ventilation and occlusion pressure responses to CO2 in healthy subjects?
Sufficiently severe expiratory impediments to breathing can enhance inspiratory muscle activity in conscious humans.
Gothe et al. (1980) studied Healthy. Expiratory resistive loads vs. Control and inspiratory resistive load was evaluated on Ventilation and occlusion pressure responses to CO2. Severe expiratory resistive loads (18 cmH2O.l-1.s) significantly increased occlusion pressure responses to CO2 and enhanced inspiratory muscle activity compared to control in healthy subjects.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: