Ultrastructural Studies on Circulating Cat Blood Platelets after in Vivo Stimulation with Collagen

This is the authors' abstract. We don't add key points for this paper.

In cats an extensive platelet aggregation in the lung was achieved by repeated intravenous injections of a collagen extract. An ultrastructural study of circulating platelets was done after one, two and several injections of collagen. When collagen injections no longer gave pressor responses in the lung vasculature, the platelets obtained from arterial blood showed pronounced changes in shape, loss of organelles and disappearance of a‐granules and mitochondria. The pronounced vacuolization with openings to the surrounding medium probably represent a release phenomenon.