Key result
Aspirin alone significantly reduced platelet aggregation induced by acid soluble collagen in healthy cats, whereas propranolol alone or in combination had no significant effect.
Why the study?
Does aspirin and propranolol alone or in combination affect hemostatic determinants in healthy cats?
Population
Healthy cats
Design
Preclinical
Authors
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Aspirin may merit investigation for feline thromboembolism prevention; hypothesis-generating and leaves open any propranolol role pending clinical trials.
Does aspirin and propranolol alone or in combination affect hemostatic determinants in healthy cats?
Aspirin alone at 75 mg every other day significantly affects platelet function in healthy cats, suggesting potential value in preventing thromboembolic disease.
Allen et al. (1985) studied Healthy cats. Aspirin and propranolol was evaluated on Hemostatic determinants including platelet aggregation. Aspirin alone significantly reduced platelet aggregation induced by acid soluble collagen in healthy cats, whereas propranolol alone or in combination had no significant effect.
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