Key result
In normal pregnancies at 11-13 weeks' gestation, arterial stiffness parameters were significantly associated with maternal age, height, and weight (p < 0.0001).
Population
Women with normal singleton pregnancies at 11⁺⁰-13⁺⁶ weeks' gestation
Design
Cohort
Authors
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Provides baseline arterial stiffness ranges in early pregnancy; leaves open validation for pre-eclampsia prediction in prospective studies.
Observational
p-value: p=< 0.0001
This study establishes normal reference ranges for arterial stiffness parameters in early pregnancy, providing a baseline to help identify abnormal hemodynamics associated with conditions like pre-eclampsia.
Khalil et al. (2012) conducted an observational in Normal pregnancy. Maternal characteristics (age, height, weight) was evaluated on Pulse wave velocity (PWV), augmentation index (AIx), and central aortic systolic blood pressure (SBP(Ao)) (p=< 0.0001). In normal pregnancies at 11-13 weeks' gestation, arterial stiffness parameters were significantly associated with maternal age, height, and weight (p < 0.0001).
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