Key result
Aortic valve replacement with the Ionescu-Shiley pericardial valve demonstrated an expected 10.5-year actuarial survival rate of 82% and a 77.5% freedom from primary tissue failure.
Population
241 patients undergoing aortic valve replacement, average age 50.8 years, 130 males and 11 females. 121 had…
Design
Cohort
Follow-up
mean 5.16 years, maximum 10.5 years
Authors
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Long-term cohort data support pericardial AVR durability; leaves open comparisons with contemporary bioprostheses.
Cohort (n=241)
Long-term evaluation of the Ionescu-Shiley pericardial xenograft in the aortic position demonstrated an 82% survival rate at 10.5 years, though structural valve deterioration and reoperation remained notable clinical events.
Revuelta et al. (1988) conducted a cohort in Aortic valve disease requiring replacement (n=241). Ionescu-Shiley pericardial valve was evaluated on 10.5 year actuarial survival. Aortic valve replacement with the Ionescu-Shiley pericardial valve demonstrated an expected 10.5-year actuarial survival rate of 82% and a 77.5% freedom from primary tissue failure.
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