Key result
The ACE insertion/deletion polymorphism distribution varied among Mexican ethnic groups, with the D/D genotype absent in Teenek and present in only 2.0% of Nahua individuals.
Population
211 healthy Mexican individuals from different ethnic groups (98 Mestizos, 64 Teenek, and 49 Nahuas)
Comparison
Determination of ACE insertion/deletion… vs Other global populations
Design
Cross-sectional
Authors
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Ethnic ACE I/D variation precludes uniform genetic risk models in Mexican patients; leaves open prospective validation for cardiovascular outcomes.
Cross-Sectional (n=211)
The ACE insertion/deletion polymorphism distribution varies significantly among Mexican ethnic groups, with Amerindian populations showing high frequencies of the I allele, which may inform future genetic susceptibility studies for cardiovascular diseases.
Vargas‐Alarcón et al. (2003) conducted a cross-sectional in Healthy individuals (n=211). Angiotensin-converting enzyme gene (ACE) insertion/deletion polymorphism was evaluated on Frequency of ACE insertion/deletion polymorphism alleles and genotypes. The ACE insertion/deletion polymorphism distribution varied among Mexican ethnic groups, with the D/D genotype absent in Teenek and present in only 2.0% of Nahua individuals.
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