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March 1, 2019Bezmialem ScienceOpen Access

Diabetes, Oxidative Stress and Endothelial Dysfunction

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Key result

Oxidative stress plays a key role in diabetic endothelial dysfunction by reducing nitric oxide levels, suggesting antioxidant agents may help ameliorate diabetic vascular complications.

Population

Diabetic patients and experimental animal models of diabetes mellitus

Design

Review

Authors

ZÖZeynep ÖZTÜRK

Discussion

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Overview

Antioxidants should not yet alter diabetes care; leaves open their role in vascular complications pending randomized trials.

Structured PICO

P
Population
Diabetic patients and experimental animal models of diabetes mellitus
I
Intervention
Antioxidant agents

This review highlights the role of oxidative stress in diabetic endothelial dysfunction and the potential of antioxidant therapies to prevent vascular complications.

Cite This Study

Zeynep ÖZTÜRK (2019) conducted a review in Diabetes mellitus. Oxidative stress plays a key role in diabetic endothelial dysfunction by reducing nitric oxide levels, suggesting antioxidant agents may help ameliorate diabetic vascular complications.

synapsesocial.com/papers/6a9fc69238b9addeebefd269https://doi.org/10.14235/bas.galenos.2017.2145
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endothelial Dysfunction in Diabetes – Clasic Sources of Vascular Oxidative Stress (Nadph Oxidases, Enos Uncoupling and Xanthine Oxidase)2013 · 1 citations
  2. 2Possible Involvement of Insulin and Oxidative Stress in Vascular Dysfunction of Diabetic Mellitus2008 · 9 citations
  3. 3Diabetes Mellitus and Vascular Endothelial Dysfunction: Current Perspectives2011 · 103 citations
  4. 4Biomarkers of Oxidative Stress in Diabetic Microvascular Complications Review Article2024
  5. 5Antioxidants, diabetes and endothelial dysfunction2000 · 272 citations