June 1, 1993The Journal of Clinical Endocrinology & Metabolism

Endothelin levels in human amniotic fluid at mid-trimester and at term before and during spontaneous labor.

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Population

Amniotic fluid samples from human pregnancies at midtrimester, at term before labor, and during labor from…

Design

Cross-sectional

Authors

MCM.Linette CaseyQueen's University Belfast CBChristine E. BrownCity Of Hope National Medical Center MPM Peters

Discussion

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Implication

Forebag-confined endothelin rise during labor supports aftereffect rather than initiator role; leaves open causal mechanisms for prospective study.

Structured PICO

Population

Amniotic fluid samples from human pregnancies at midtrimester (n=38), at term before labor (n=33), and during labor from the upper compartment (n=40) and forebag (n=125).

Outcome

Immunoreactive endothelin (irET) levels in amniotic fluidsurrogate

Increases in amniotic fluid endothelin at parturition are confined to the forebag, suggesting it is an aftereffect of labor rather than an initiator of parturition.

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Casey et al. (1993) studied this question.

synapsesocial.com/papers/6a9fcdcc216b4ce72bba4f5f https://doi.org/10.1210/jcem.76.6.8501173

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Implication

Forebag-confined endothelin rise during labor supports aftereffect rather than initiator role; leaves open causal mechanisms for prospective study.

Endothelin levels in human amniotic fluid at mid-trimester and at term before and during spontaneous labor.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Endothelin levels in human amniotic fluid at mid-trimester and at term before and during spontaneous labor.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider