Population
Pregnant women at various stages of pregnancy, labour, and post-delivery, and non-pregnant women
Design
Cohort
Authors
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ir-ET levels fluctuate during pregnancy and delivery; hypothesis-generating for its hormonal role, requiring prospective confirmation before any clinical implications.
Immunoreactive endothelin concentrations fluctuate significantly during pregnancy and labour, suggesting it may act as a circulating hormone in both maternal and fetal circulations.
Iwata et al. (1991) studied this question.
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