Population
Normal pregnant women at various stages of gestation, during labor, and postpartum.
Design
Cohort
Authors
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ET-1 elevation in labor warrants no clinical action; leaves open its role in parturition or fetal development.
Endothelin-1 levels increase during pregnancy, peak during labor, and are highly concentrated in amniotic fluid, suggesting a potential physiological role in labor or fetal development.
Usuki et al. (1990) studied this question.
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